Are There Effective Alternatives To Adderall?

Medically Reviewed By

Dr. Po-Chang Hsu

Dr. Po-Chang Hsu

On October 28, 2024

Written By

Amanda Stevens

Amanda Stevens, B.S.

On October 28, 2024

What you will learn

  • Adderall is a common medication prescribed for ADHD, but as a Schedule II controlled substance, it poses risks of dependence and misuse.
  • ADHD symptoms include inattention, impulsivity, disorganization, and mood swings.
  • Prescription alternatives to Adderall include non-stimulant medications like Strattera and Wellbutrin.
  • Natural supplements, such as vitamins, minerals, amino acids (and derivatives), essential fatty acids, and herbal supplements or botanicals, may also be beneficial for ADHD symptoms.
  • Long-term Adderall use can lead to significant health risks, including cardiovascular issues and other psychiatric symptoms.
  • Although natural alternatives' treatment outcomes and effectiveness may vary, they are associated with fewer serious side effects in some cases.
  • Always consult a healthcare professional before trying non-prescription options or altering your medication regimen.
  • ADHD patients may also find relief from symptoms through lifestyle changes, such as exercise, a healthy diet, and a consistent sleep schedule.
  • Professional treatment options for ADHD include detox, residential programs, and outpatient services.
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Adderall is a pharmaceutical intervention for treating Attention Deficit Hyperactivity Disorder (ADHD). It is a central nervous system (CNS) stimulant medication that can result in focus enhancement, cognitive improvement, and concentration, making it easier for those with ADHD to navigate work, academics, or any aspect of daily life.

However, Adderall is classified as a Schedule II controlled substance, meaning regular use can increase the chances of dependence and misuse.[1] Many struggling with ADHD symptoms seek alternatives to Adderall that are not associated with this significant risk. While everyone is different, and what works for you may not work for another, several Adderall alternatives offer promising results.

Before making any medication changes or altering your daily regimen, consult the prescribing physician or your primary care provider.

Are there prescription-based alternatives to Adderall?

Yes, other prescription medications are available for treating ADHD. Adderall and other stimulant ADHD medications like Vyvanse, Ritalin, and Concerta are still widely considered the first-line intervention for ADHD. A nonstimulant medication or medications without amphetamines would be considered second-line interventions.

Despite the absence of stimulants, several alternatives to Adderall are associated with similar results. In a thorough study conducted to explore non-stimulant treatment for attention deficit hyperactivity disorder, many patients who received non-stimulant alternatives to Adderall showed marked ADHD symptom improvement.[2]

These prescriptions include Alpha-2 noradrenergic agonists, selective norepinephrine reuptake inhibitors, Tricyclic antidepressants,  Non-scheduled stimulant medications, and Non-tricyclic antidepressants, among others.[3] Specific examples of prescription alternatives to Adderall for ADHD include:

  • Atomoxetine (Strattera)
  • Bupropion (Wellbutrin)
  • Clonidine (Kapvay)
  • Guanfacine (Tenex)
  • Modafinil (Provigil)
  • Venlafaxine (Effexor)
  • Viloxazine (Qelbree)

What are the long-term effects of Adderall use?

Long-term use of ADHD stimulant medications like Adderall is associated with some mental and physical health risks, including:[4]

  • Risk of dependence and misuse
  • High blood pressure and elevated heart rate
  • Cardiovascular issues
  • Increase in psychiatric symptoms
  • Increased risk of seizures
  • Increased risk of serotonin syndrome when taken with other serotonergic drugs
  • Developing a tolerance to Adderall

Does Adderall have serious side effects?

Serious side effects of Adderall are rare but may include:[5]

  • Heart issues
  • Mental or cognitive issues
  • Poor circulation
  • Increased risk of seizures or convulsions
  • Twitchy muscles or nervous tics
  • Changes to vision

What are some non-prescription alternatives to Adderall?

Non-Prescription Alternatives to Adderall

Yes, there are natural alternatives to Adderall that may be a good fit for anyone who wishes to avoid prescription-based treatments or stimulant medications. Some alternative interventions include botanical agents, natural supplements, nootropics, and adaptogens. The appeal of a natural approach can be to exert more control over your treatment and make adjustments on your own.

It’s important to note that some of the natural alternatives to Adderall aren’t regulated, and physicians often have lower confidence in their effectiveness. They may also carry the Food and Drug Administration (FDA) safety warnings. Before testing any unregulated supplement or natural alternative to Adderall that the FDA does not approve, speak with your doctor.

Despite these mild cautions, medical studies have been conducted to explore natural alternatives to Adderall (either as standalone interventions or combined with other substances) better to understand the effectiveness, potential, and safety. Some natural Adderall alternatives include:[6]

  • Vitamins
      • Vitamin C
      • Vitamin B6
      • Vitamin E
      • Tocotrienols
      • Vitamin B6 and Magnesium combination
  • Mineral Supplements
      • Iron (ferrous sulfate)
      • Magnesium
      • Calcium
      • Zinc (zinc sulfate)
  • Amino Acids (and derivatives)
      • Acetyl-L-carnitine
      • Glycine
      • Taurine
      • GABA (Gamma-Aminobutyric Acid)
      • 5-HTP (5-Hydroxytryptophan)
      • L-theanine
      • L-tyrosine
  • Essential Fatty Acids
      • EPA (Eicosapentaenoic acid)
      • DHA (Docosahexaenoic acid)
      • Omega-3 Fatty Acids
      • Omega-6 Fatty Acids
  • Herbal Supplements or Botanical
      • Bacopa (Bacopa monnieri)
      • Ginkgo biloba
      • Ginseng
      • Ningdong (Traditional Chinese Medicine remedy)
      • Passion Flower
      • Pycnogenol® (French maritime pine bark extract)
      • St. John’s Wort (Hypericum perforatum)
      • Valerian (Valeriana officinalis)
      • Thyme Oil

How effective are these alternative treatments, and what are the potential benefits and drawbacks?

The study above covered all the listed categories of substances and recorded the treatment outcomes and side effects of these natural interventions. Treatment outcomes were most successful with combination interventions but included a varying range of the following benefits:[7]

  • Improvements in ADHD symptoms (restlessness, self-control, attention, concentration, brain function, etc.)
  • Reduced impulsivity, hyperactivity, aggression, and anxiety
  • Improved overall quality of life

Some cautions and side effects of these natural interventions were either nonexistent or minimal but included:[8]

  • Mild stomach upset
  • Sleepiness
  • Appetite loss
  • Nausea
  • Constipation
  • Metallic taste (Zinc)

How can individuals make informed choices about non-prescription options?

You know your body and your experience better than anyone. Being actively involved in your treatment process benefits long-term adherence to treatment protocols and success. Stay informed about the latest treatment options and therapeutic modalities that can improve cognitive function and offer other tangible benefits for ADHD.

Educating yourself allows you to become your advocate and foster a collaborative relationship with your provider. Working with a treatment professional, you can try different strategies and document your physical, mental, and emotional reactions to determine what is best for you.

What are beneficial lifestyle changes that can improve ADHD symptoms?

Also, consider non-medication or supplement-related solutions to treat ADHD, like regular exercise and other lifestyle changes, including a balanced and healthy diet, structured daily routines, a consistent sleep schedule, self-care practices, aromatherapy, and limiting screen time offer holistic benefits that may ease the experience of managing ADHD symptoms. [9]

Treating ADHD Symptoms: Why are prescription or natural alternatives needed?

The symptoms associated with attention deficit hyperactivity disorder (ADHD) can range from mildly disruptive to debilitating and include:[10]

  • Inattention
  • Disorganized
  • Inability to finish tasks
  • Avoidance of exertion or effort
  • Always losing things
  • Forgetful
  • Fidgety and restless
  • Loud
  • Impulsive
  • Impatient
  • Procrastination
  • Mood swings
  • Low self-esteem

Medications and supplements that alleviate this disorder can relieve the internal chaos and help you be more productive. Finding the right intervention for you requires medical or psychiatric assistance.

Professional Treatment For ADHD & Other Mental Health Conditions

If you or a loved one are struggling with Adderall abuse or substance misuse, seek professional help for both substance use and mental health conditions. Our approach to treatment is discrete and effective, offering both short-term and long-term solutions that improve symptoms and elevate your lasting potential. ADHD and substance use disorder treatment programs include:

  • Detox: Detoxification is a medically monitored stabilization program that offers practical symptom relief while also eliminating harmful substances from your system. Once you’re stable, we will begin implementing other treatments for long-term success.
  • Residential Treatment Program:Get away from the distractions of life and focus solely on your healing and recovery. Here, you will have 24/7 support, a community of peers, and daily treatment to help you recover.
  • Intensive Outpatient: After residential treatment, an intensive outpatient program offers a structured but flexible solution for treatment. In this program, you can live at home and maintain some of your daily routines without sacrificing the support or treatment you need.
  • Alumni Services: Our alumni services provide long-term support after formal substance use disorder treatment is over. Here, you will connect with others pursuing recovery, build practical relapse prevention skills, and find healthy coping methods.

Frequently Asked Questions About Alternatives To Adderall

Can an OTC Adderall alternative be taken along with other supplements?

Over-the-counter medications and supplements can help treat ADHD symptoms, but the answer to this question varies from person to person. It’s easier to determine what is safe for you to take after knowing all of the supplements or medications you may be taking. Speak with a treatment professional to discuss your options and potential drug interactions.

What are the top 4 ADHD medications?

The most common ADHD medication options are Adderall, Ritalin, Vyvanse, and Concerta. They are all prescribed in various doses and on different dosing schedules. However, all are Schedule II controlled medications and associated with a higher risk of dependence and substance abuse.

What over-the-counter alternatives to Adderall stimulants can enhance energy?

There are some natural energy boosters that those pursuing ADHD treatment may find beneficial, including [11]

  • Ashwagandha
  • Rhodiola Rosea
  • Vitamin B12
  • Iron
  • Melatonin
  • CoQ10
  • Creatine
  • Citrulline
  • Beetroot Powder
  • Tyrosine
  • Caffeine With L-Theanin

Ascendant New York Editorial Guidelines

Here at Ascendant New York, we understand the importance of having access to accurate medical information you can trust, especially when you or a loved one is suffering from addiction. Find out more on our policy.

Sources

[1]Drug scheduling. DEA. (n.d.). https://www.dea.gov/drug-information/drug-scheduling

[2][3]Budur, K., Mathews, M., Adetunji, B., Mathews, M., & Mahmud, J. (2005, July). Non-stimulant treatment for attention deficit hyperactivity disorder. Psychiatry (Edgmont (Pa. : Township)). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3000197/

[4]Adderall® CII (Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate and Amphetamine Sulfate Tablets (Mixed Salts of a Single Entity Amphetamine Product)). accessdata.fda.gov. (n.d.). https://www.accessdata.fda.gov/spl/data/7853fa49-c842-4de6-a1f2-fffd03a755a9/7853fa49-c842-4de6-a1f2-fffd03a755a9.xml#LINK_4d3067b7-ce74-4448-ac19-d12c4f393e0c

[5]Adderall: Uses, dosage, Side Effects & Safety Info. Drugs.com. (n.d.-a). https://www.drugs.com/adderall.html

[6][7][8]Ahn, J., Ahn, H. S., Cheong, J. H., & Dela Peña, I. (2016). Natural product-derived treatments for attention-deficit/hyperactivity disorder: Safety, efficacy, and therapeutic potential of combination therapy. Neural plasticity. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757677/

[9]Lifestyle Strategies for Adult ADHD. My Doctor Online. (n.d.). https://mydoctor.kaiserpermanente.org/ncal/article/lifestyle-strategies-for-adult-adhd-2000316

[10]Magnus, W. (2023, August 8). Attention deficit hyperactivity disorder. StatPearls [Internet]. https://www.ncbi.nlm.nih.gov/books/NBK441838/

[11]Walle, G. V. D. (2018, May 28). The 11 best vitamins and supplements to boost energy. Healthline. https://www.healthline.com/nutrition/best-supplements-for-energy